BIOREADER® 7000 -E
Our Bioreader® counts 100% of the filter area! No losses due to the exclusion of the outer border/filter region.
The BIOREADER® 7000 -E is the best ...
BIOREADER 7000-V
BIOREADER® 7000 -V
For non-fluoro applications in 384 well to 6 well plates and Petri dishes.
Using the BIOREADER® 7000 -V you may analyze enzymatic Elispot in 96 well plates as well as other applications liek Plaque/FOCI in different multiwell plates.
With common fixed focal length objectives also other plate types in full field-of-view are possible: 6- to 1536 well plates, Terasaki plates, upt to 100 mm Petri dishes and cell culture bottles (like T-Flask).
And they provide a resolution of: 100 - 2000 µm for FOCI, 100 - 5000 µm for Plaques or 50 - 2000 µm for cell clones.
The automatic objective changer and camera focusing are software-controlled.
This Bioreader® is able to quantify visible stain. For instant CV, DAB (3,3′-Diaminobenzidine), Substrates TMB,PCIP/NBT, AEC
Model variants:
Basic: 12 MPixel camera, 1 fixed focal length objective, for example for 96 well plates (with high resolution), as well as 48 and 24 well plates (with lower resolution).
Alpha: 5 MPixel camera, 2-times objective changer, for example for 96 and 24well plates with high resolution (with high resolution).
Beta: 5 MPixel camera, 3-times objective changer, for example for 96, 24 and 6 well plates with high resolution (with high resolution).
Gamma: 5 MPixel camera, 4-times objective changer, for example for 96, 24 6 well plates and 50 mm cell culture plates (with high resolution).
Tests of antiviral substances
This Bioreader® and EazyReader® support testing and development of antiviral substances.
Example#1: The automatic analyses of Plaque reductions assay.
This assay applies diluted doses of a -possibly- antiviral drug into multiwell plates. The Bioreader automatically observes its capability to suppress the formation of plaques (-holes-) in the bacterial lawn.
The ‘Plaque reductions neutralization test’ (PRNT) is a variation of this test. It is an attempt to find an antibody that neutralizes a specific virus. This is a very valuable tool in antiviral vaccine research.
Examplel#2: The automatic evaluation of the Yield reduction assay
In several steps of operation cells are infected in presence of variable doses of a possibly antiviral drug substance.
Thereafter the virus titer is determined in the liquid by use of the plaque or TCID50 assay with of the Bioreader®.
The titer is calculated as the quotient of the positive cells/all cells, taking in account the virus dilution factor and the volume of the inoculum.
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BIOREADER® 7000 -FFluoro Elispot/Plaque + Enzymatic Readers for 96 wells with innovative power LED fluoro excitation. This BIOREADER® 7000 -F allows you to evaluate verifie...
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EAZYREADER® 7000World's first 100 % scalable Elispot/Plaque Reader that may be upgraded on-site to a Single Cell/PBMC counter. Basic functionality (Core Unit) of the EazyReader® 70...
