Rabbit monoclonals: Combining the high affinity of rabbit antibodies with the specificity of a monoclonal

Recombinant monoclonal antibodies are primary antibodies manufactured via cloning antibody-coding genes into high-yield expression vectors, subsequently introduced into expression hosts. This overcomes the limitations of other antibody manufacturing methods, such as genetic drift (in hybridoma production), which can lead to lot-to-lot variation. Abcam’s RabMAb® recombinant technology combines the antigen recognition of the rabbit immune system with the specificity of a monoclonal antibody.

Learn why RabMAb® technology:

  • Provides higher affinity and specificity compared to traditional antibodies
  • Often gives lower background signal compared to traditional antibodies
  • Provides diverse epitope recognition
  • Is ideal for studying mouse models
  • Is ideal for demanding applications like IHC on FFPE tissue

The RabMAb® advantage

  • Diverse epitope recognition
  • Improved immune response to small-size epitopes
  • High specificity and affinity
  • Improved response to mouse antigens

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