a newchromogenic DNAin situhybridization (ISH)technology. DNAscope™ employs the proven “double-Z” probe design and signal amplification system of RNAscope™, enablingrapid and flexi...
Basescope Assay
Visualize a specific RNA locus at single cell sensitivity with spatial and morphological context
The BaseScopeTM Assay is a unique product from ACD, based on the same platform of proven and established RNAscope® technology that has been cited in over 900 publications in just 5 years. This powerful assay provides new data dimensions and unique insight into biological mechanisms. The BaseScopeTM Assay enables applications such as the detection of exon junctions/splice variants, short/highly homologous RNA sequences (50-300 bases), and point mutations at single cell sensitivity.
- Detecting biological events in cells and in situ using a single Z pair
- Highly specific and sensitive detection of RNA targets with down to ONE nucleotide differences
- Analysis of broad sample types: FFPE cells & tissues (TMAs), Fresh or fixed frozen tissues, Cultured cells
| Exon Junctions / Splice Variants | Short Sequences | Point Mutations |
|---|---|---|
| Exon Junctions / splice variants | Short / highly homologous gene sequences (50-300nt) | Point Mutations (ACD validated point mutations only) |
| Circular RNA (circRNA) | T cell receptors (TCRs) and CDR sequences in T-cell clones | Short InDel |
| Gene fusion | Gene editing / CRISPR | Homologous |
| Gene knockout (KO) | Pre-miRNA | |
| Microexons | ||
| Small nucleolar RNA (snoRNA) |
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Four flexible solutions for all your research needs Independent of your genes of interest, our easy RNAin situhybridization assay uses common reagents and protocols; providing univ...
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Introducing the highly specific and sensitive miRNAscope™ Assay to detect small RNAs with spatial and morphological context at single-cell resolution. Leveraging ACD’s RNAscope™ co...
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RNAscope™ Plus smRNA-RNA Assay Small regulatory RNAs, including miRNAs, are instrumental in regulating human health and have been associated with a wide range of differe...
