PanCancer Pathways

nCounter PanCancer Pathways Panel

Drawing on 30+ years of cancer research, QPCR, Next Generation Sequencing, Gene Expression, Western blotting the cancer community has accomplished a lot to narrow tens of thousands of genes to the ones that matter for the study of cancer.

Today, we are taking the next step in that journey with the introduction of our PanCancer Pathways Panel, a novel set of 700 essential genes representing all major cancer pathways including key driver genes.

Using a biology-guided, data-driven approach and applying basic co-expression principles we scored and ranked each gene based on its biological relevance to cancer and its role as an essential representation in one or more of the 13 canonical pathways.

We can now take this very complex disease and make it a bit easier to comprehend to
Discover connections. Discover interactions. Discover function.

Pathways of the PanCancer Pathways Panel

770 Essential Genes Representing 13 Canonical Pathways

  • 606 Pathway Genes:
    Notch, Wnt, Hedgehog, TGFB, MAPK, STAT, P13K, RAS, Chromatin Modification, Transcriptional Regulation, DNA Damage Control, Cell Cycle, Apoptosis
  • 124 cancer driver genes
  • 40 reference genes
  • Customize with Panel-Plus option flexibility to include 30 genes of your choice

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