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Custom Oligo Synthesis

KareBay Bio™ provides various high-quality oligonucleotides with good raw materials, advanced biolytic synthesizer, optimized process and professional scientists. Quality of the oligonucleotides are all managed and guaranteed with strict quality control system. For any specific requirements, we also offer custom DNA oligonucleotide modification services. The oligonucleotides can be applied not only in gene synthesis, but also in biochips, sequencing, genome amplification and large-scale gene cloning and expressions.

Our advantages:

Premium quality & high purity
Quality and purity of all the oligonucleotides from KareBay are guaranteed with strict quality control system. KareBay Bio™ has various advanced synthesizer, such as BLP platform, which is mainly used with SpectraMax for high-throughput synthesis. Additionally, KareBay also has ABI 3900 and BioAutomation, which is mainly used for large-scale synthesis. Also, KareBay has various models of HPLC instruments to purify 50nmol – 50umol products once and the purity is 95% or above.

Short turnaround time & fast delivery
Standard oligonucleotides will be synthesized and dispatched with 2 working days. DSL/OPC purified oligonucleotides (≤ 60 bases) usually take 1-2 working days. For PAGE/ HPLC purified oligonucleotides, it usually costs 2-3 working days. Modified oligonucleotides will take 5-7 working days.

Diverse purification methods
 DSL purification/ C18 desalination;

 OPC purification;

 PAGE purification;

 HPLC purification

High stability
For synthesizing high OD oligonucleotides, KareBay uses freeze-drying technology. Compare with utilizing vacuum drying oven, the oligonucleotide products treated with freeze-drying technology have less damage and the lyophilized products can be stability stocked at -20°C for up to one year or reserved at 4°C for several months.

Various modification available
KareBay provides various high-quality fluorescent modification services, including dual-labeled fluorescent probes, rare bases, phosphorothioated oligos, phosphate groups, various fluorescent group modifications, biotin and digoxin.


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