เครื่องอ่านลำดับเบสแบบ Next Generation Sequencer

Discover the AVITI™ System Family

Flexible and High-Quality Sequencing and Cytoprofiling Solutions from Element Biosciences

Powered by Avidity Base Chemistry

Our AVITI line of systems are built on avidity base chemistry (ABC), enabling unparalleled accuracy and efficiency in nucleotide detection. By utilizing a unique combination of enzymatic and chemical processes, ABC enhances the specificity and sensitivity of base calling, resulting in high-fidelity sequencing data with minimal errors. This innovative technology enables researchers to confidently explore the complexities of the genome, from identifying rare variants to unraveling intricate genetic pathways.

AVITI

The AVITI system conducts cost-effective, high-quality sequencing across a wide range of applications, without the hassle of batching. Whether it's 100 million reads or 2 billion, AVITI delivers flexible throughput at exceptionally low cost, saving you time and resources without compromising performance. The AVITI can be upgraded to the multiomic capabilities of the AVITI24.

 

AVITI LT

AVITI LT is a low-throughput version of AVITI that brings high-quality ABC sequencing to more users with its lower instrument cost. AVITI LT is the ideal choice for smaller-scale projects or research labs with a small range of applications or limited capital equipment budget. AVITI LT delivers high-quality sequencing with the flexibility to upgrade to the full-throughput AVITI or the multiomic capabilities of the AVITI24.

 

AVITI24

AVITI24 brings a new era in scientific exploration by seamlessly integrating state-of-the-art sequencing and CytoProfiling with Teton™ into a single platform. With AVITI24 Teton, you can now analyze DNA, RNA, proteins, phosphorylated proteins, and cell morphology simultaneously from just one sample at single cell resolution.

 

Cloudbreak UltraQ™: Enhanced Sequencing Accuracy When Precision Matters Most

Pushing the potential of the AVITI™ system even higher, we are excited to introduce Cloudbreak UltraQ for enhanced accuracy when precision matters most. Cloudbreak UltraQ sets a new standard for data quality with >70% of reads Q50 or above (>99.999% accurate) when benchmarked with CHM13 human cell line PCR-free libraries against the T2T gapless human reference genome.

Figure 1. UltraQ produces highly accurate data for PCR-free CHM13 libraries in both read 1 (left) and read 2 (right) with predicted Q scores that closely match recalibrated Q scores, with no masked genomic regions.

A New Standard for Data Quality

Improving sequencing accuracy beyond our already high-performing Cloudbreak chemistry required improvements to the sequencing chemistry, mitigation of library prep introduced errors, and thoughtful handling of analysis artifacts for reliable benchmarking. Learn more about our approach and how we evaluated this new chemistry.

Read the blog

Explore the datasets

Rooting out Error at the Source

Watch our VP of Informatics Semyon Kruglyak, PhD, describe how we characterized and identified sources of error beyond sequencing itself and devised innovative ways to address those sources of error at their root.

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