MACS® Cell Culture and Stimulation Products

Our MACS® Cell Culture and Stimulation portfolio comprises a specialized and versatile range of cell culture media and reagents for cell stimulation, expansion, and/or differentiation. Products are available for human and mouse primary cells, including immune, stem, neural, and tumor cells. Furthermore, small molecules and reprogramming reagents are available for stem cell research.

Cell culture media 

We offer cell culture media optimized for specific cell types. 

MACS® Media are designed and quality tested for reliable and consistent results. For optimal performance and standardization, all recombinant cytokines and growth factors used in our media are produced in house. Choose from the categories below to find the right cell culture media for your stem cell, neuroscience, cancer, and immune cell research. 

Recombinant cytokines and growth factors for cell cultivation

Our recombinant cytokines and growth factors are available in three quality grades: 
research grade, premium grade, and MACS® GMP Grade. 

With research and premium grade, we offer a comprehensive portfolio of cytokines for reliable research with human and rodent cells. MACS Premium-Grade Cytokines are standardized recombinant proteins of highest quality, which facilitate a seamless transition to clinical research with MACS GMP Cytokines. Furthermore, the given biological activity of each premium-grade cytokine batch enables exact unit dosing and eliminates laborious pre-testing on your end. 

Cell stimulation reagents for effective cell activation and expansion

Miltenyi Biotec offers reliable tools for both antigen-independent and antigen-specific cell stimulation of a variety of target cells. 

Our product portfolio ranges from polyclonal stimulation reagents, over ligands for toll-like receptors (TLRs), to recombinant proteins and overlapping peptide pools. MACS® Stimulation Reagents enable effective cell activation and expansion and ensure a reliable experimental outcome.

Small molecules for modulating cultured stem cells

StemMACS™ Small Molecules are invaluable tools for modulating cellular reprogramming, stem cell self-renewal, and differentiation. As low molecular weight compounds, small molecules can effectively penetrate the cell membrane to activate or inhibit key signaling pathways within the cell. Effects can be easily fine-tuned by varying the molecular concentration. Their chemically defined nature ensures defined cell culture conditions and offers consistent biological activity with each lot.

Our small molecules are rigorously tested by HPLC and mass spectrometry to guarantee highest purities. They are designed for use with stem cell cultures and are an ideal, cost-effective complement to MACS® Cytokines and Growth Factors.

mRNA transfection for stem cell differentiation and reprogramming

mRNA transfection is a powerful tool for modulating cell fate while eliminating the risk of insertional mutagenesis. Using simple lipid-based transfection, modified mRNAs are delivered into the cell allowing high-level, transient expression of key developmental regulators, recombinases, or markers. This pioneering non-integrative mRNA technology has revolutionized reprogramming of somatic cells and offers new approaches for direct programming and differentiation of stem cells.

Viral transduction reagents and cell culture matrices

Boost viral transductions of hard-to-transduce cell types such as suspension cells using Vectofusin®-1. The fully synthetic peptide offers a straightforward protocol which can be easily adopted from small to large volume transductions. Eliminating the need for pre-coating, Vectofusin®-1 provides more flexibility in experiment planning and can be easily integrated into automated processes. Vectofusin®-1 is also available in MACS® GMP Grade.

Cell culture matrices support cell attachment in cell culture applications. Our Recombinant Human Fibronectin (Fragment), premium grade is a defined extracellular matrix protein perfectly suited for various applications such as culture of primary endothelial cells, mesenchymal stem cells, or stem cell derivatives such as cardiomyocytes or neuronal cells.

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