Featuring patented microchip-based sorting technology, the MACSQuant Tyto fully encapsulates cell sorting in an easy-to-use sterile cartridge. Cell sorting with the MACSQuant Tyto is truly gentle, happening at low pressure, under mild shear forces, and without decompression or charge. The MACSQuant Tyto is equipped with three lasers to facilitate multiparameter flow sorting at high speed and without aerosol formation. The safe containment and simple walk-away operation elevates sorting of fragile cells – even in hazardous materials or GMP environment – to a new standard for basic and traslational research and medical applications.